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No participants developed antibodies against AOD-9604, and no treatment-related serious adverse events led to study withdrawal

Understanding your genetic predisposition helps your provider fine-tune dosing and rotation timing for optimal absorption and fewer side effects

Use species-level signals (e.g., DHE-HPLC for O 2 via 2-OH-E, compartment-targeted HyPer/roGFP-Orp for H 2 O 2 , peroxiredoxin redox state as a fast sentinel) to attribute source and location, use footprints (F-isoprostanes, protein carbonyls/nitrotyrosine, 8-oxoG) to gauge exposure, add buffer indices (GSH/GSSG, TAC) and iron axis (labile iron pool, oxidized phospholipids, GPX4 context) to estimate OH/ferroptosis propensity